Climate change threatens humanity and the planet on which we live. Social inequities, including startling variance in the health outcomes that different population groups enjoy, also pose a threat to humanity, although less directly. Together, the scale of devastation these threats pose is unprecedented…but wholesale destruction is not inevitable. Humanity can and must act to prevent catastrophic climate change and redress egregious global health inequities. It must act now. With a focus on disrupting the existing ‘consumptagenic system’, this talk outlines some of the steps necessary to move from inertia towards effective and equitable climate change adaptation and mitigation through progressive public policy, sustainable business models and effective social mobilization.