Hydroxyapatite coatings for titanium implants

Researchers at ANU have developed a novel one-step manufacturing process that produces a highly osseointegrative, robust hydroxyapatite coating that promotes growth of bone into the implant surface.


Current hydroxyapatite coatings, commonly applied to titanium implants, facilitate osteoconduction or development of bone adjacent to the implant surface, promoting rapid fixation and bonding of the bone to the implant.  However, the current FDA approved method for manufacturing hydroxyapatite coatings produces a surface that that does not fully mimic the natural structure of hydroxyapatite in bone, and can become unstable in vivo over time. 

The innovation

ANU researchers have developed a one-step manufacturing process that produces a robust hydroxyapatite coating that closely mimics the natural structure, and promotes growth of bone cells into the implant surface, a process called osseointegration. The process is rapid, scalable and economical, and will lead to better device integration and reliability, offering great benefits to the orthopaedic implant market internationally.

This new coating process is relevant to the medical ceramics market which is projected to reach US$16.3 billion by 2020, registering a CAGR of 6.4% between 2015-2020. The medical ceramics market is driven by the orthopaedic and dental implant market which was valued at US$34.0 billion in 2013 and is expected to grow to approx. US$45.4 billion in 2021.

Partnering opportunity

ANU is seeking feedback and engagement from interested industry partners on the HAp technology. ANU is interested in establishing a collaboration with a licensee with demonstrated pathway to market capability and experience in the various phases of development and regulatory requirements.