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Honours Projects 2006

To obtain a detailed description of each project please contact Dr Susan Howitt for a copy of the Honours Handbook.

Supervisor Co-Supervisor Honours project title

Dr Gwen Allison

 

  Further screening of the isolates and characterisation of traits involved in survival in the gut
Molecular characterisation of S-layer genes and proteins produced by lactobacilli originating from the chicken GIT
Identification and characterisation of novel species from the chicken GIT
Dr Joseph Altin   Determine whether the targeted stealth liposome approach can be used to target the delivery and expression of DNA to dendritic cells in vivo
Assess whether the approach can be used to either enhance immunity (eg. to cancer) or to induce tolerance (eg. to antigens of relevance to autoimmune diseases).
Dr Carolyn Behm

 

 

 

Investigation of the function of genes of (currently) unknown function
Stephen Trowell Molecular olfaction using C. elegans as a model organism
Dr Ulrike Mathesius A worm's view of the bacterial world
Dr Stefan Broer   Novel brain amino acid transporters
Structure-function relationships in the Neurotransmitter transporter family
Prof Kiaran Kirk Projects involving expression of transporters from the malaria parasite
Dr Aude Fahrer   Identifying condensin II interacting proteins .
Further characterising the T cell developmental defect in the nessy mouse
Understanding the alternative transcripts of the mutated gene.
Characterising functional T cell defects in the nessy mouse

Prof Adrienne Hardham

David Jones The role of cell wall degrading enzymes in Phytophthora infection of host plants
Leila Blackman Analysis of the role of zoospore motility in plant infection
Leila Blackman & Andrea Robold Characterisation of the Phytophthora spore adhesive
Dr Susan Howitt   Genetic analysis of interactions within sulphate transporters
Prof Kiaran Kirk Expression and analysis of members of the folate transporter family from the malaria parasite in yeast.
Dr.Dean Price Structure and function of cyanobacterial bicarbonate transporters
Cyanobacterial Genetics: Rapid evolution by Lateral Gene Transfer?
Dr.Lynn Jones & Prof Robert Saint Robert.Saint@anu.edu.au   Test the possibility that the sister protein kinases, Wee1 and Myt1, regulate the Pav motor protein by phosphorylating it.
Dr. Javier G.Fernandez-Velasco   The study of the biology of H 2 production/assimilation in C. reinhardtii in order to clarify the physiological role of the hydrogen metabolism in C. reinhardtii .
Prof Kiaran Kirk Dr Rowena Martin Amino acid transport in the malaria parasite
A novel channel encoded by the malaria parasite
Dr Pauline Junankar and Dr Rongwei Teng Metabolic profiling of the malaria parasite
Dr Kevin Saliba The mechanism of chloroquine resistance in the malaria parasite
Dr Richard Allen Novel channels induced by the parasite in the human erythrocyte membrane
Dr Rowena Martin and Dr Susan Howitt Expression and analysis of members of the folate transporter family from the malaria parasite in yeast
Dr Ulrike Mathesius Dr Carolyn Behm A worm's view of the bacterial world
Prof. Helen O'Neill   Leukemic stem cell
Development of dendritic cells in spleen
Dr Barry Pogson   Characterising plants that are resistant to environmental stress, such as drought and excess light
Plant Development and Carotenoid Biosynthesis.
Studying the function of novel transcription factors on photoprotection and photosynthetic acclimation to altered light regimes (in collaboration with Murray Badger, RSBS).
Dr Sadiq Rahman & Dr Zhongyi Li & Dr Peter Chandler   Grain mutants a proteomic, genomic and chemical analysis.
Kevin Saliba   Localisation and knockout of the malaria parasite's H + -pyrophosphatases
High throughput assay for the identification of drugs that interfere with parasite pH regulation

Dr Louise Tierney

  Distinguishing between a structural or functional role for the conserved cysteine loop.
Determining the role of the cysteine loop in the moloecular gating mechanism and the binding of anaesthetics in GABA A receptors.
Functional consequences of clustering GABA A receptor and the physical interactions underlying clustering.
Dr Barbara Van Leeuwen & Dr Peter Kerr   Host-virus coevolution
The immune response to viral infection involves both cellular mediators and soluble factors called cytokines.
Dr Naresh Verma   Structure and function studies of glucosyltransferases (O-antigen modification genes) encoded by serotype-converting bacteriophages of Shigella flexneri
Role of O-antigen modification in S. flexneri virulence
Vaccine design against Shigellosis