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Research School of Biology
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MSDS's (Material Safety Data Sheets) MSDSs contain all the information that is known about a chemical, including physical properties, health hazards, first aid and precautions for safe handling. All chemicals should have an MSDS, but not all are considered hazardous. However, many chemicals classified as Non-hazardous may still harm your health if not handled with appropriate precautions, so read the information provided and take appropriate precautions. Each laboratory has a red MSDS folder which contains: Prior to commencing any lab work, you should read the MSDS for each chemical you will use, and complete a risk assessment for any of the hazardous chemicals. You will then have the information you require to reduce/eliminate any risks involved, and know how to react in the case of an emergency -for your own and your co-workers safety. Acquiring MSDSs Put any MSDSs that you have printed or received in the MSDS folder. If you have any queries regarding MSDSs, risk assessments or safety precautions for handling particular chemicals, then do not hesitate to contact Ginny Sargent or Garry Mayo. Information to Help Interpret MSDSs A. Product Identification and Hazard Coding
Ingredients: Lists the ingredients of the product and their proportions or concentrations in a mixture D. G. Class: Dangerous Goods Class refers to the health and safety hazards of the substance, eg DG 8 is a flammable substance Subsidiary Risk: is shown if the material has another significant hazard in addition to the primary hazard. Packaging Group: is another subset of the D G Code. D G of Class 3, 4, 5, 6.1, 8, and 9 are further divided into three groups according to the degree of risk:
HAZCHEM: The HAZCHEM code provides information for fire fighters/emergency teams on best fire-fighting medium, risk of violent reaction, personal protection, spillage control, and need to evacuate nearby community. Poisons Schedule: National Health and Medical Research Council (NHMRC) schedule number defines the level of retail restriction of material. B. Physical Properties Boiling Point: This gives a strong indication of the likely vapour concentration above a liquid Melting Point: Is the temperature at which the material converts from a solid to a liquid Specific Gravity (sg): The density of a liquid relative to water (water sg=1). A water immiscible floats on water if its sg<1, but sinks if its sg > 1. The sg also refers to the weight, eg 1L of Acetone (sg=0.79) weighs 0.79kg. Vapour Pressure: is the pressure of vapour in equilibrium with the liquid at a given temperature. The data allows a calculation of the saturated vapour concentration from the liquid in the absence of ventilation.
= 24% This figure can be usefully compared to the lower explosive limit and the occupational exposure standard. Flash Point: The temperature at which a flammable liquid will have sufficiently high vapour pressure to burn (ie reach its lower flammability limit) Flammable (explosive) Limit: The range of concentration of a flammable vapour in air that will burn or explode in the presence of an ignition source. Auto Ignition Temperature: The temperature at which combusiton starts in the absence of an ignition source Relative Vapour Density: The density of a fas or vapour relative to air (air =1). A fas/vapour of density > 1 may flow and sink and remain concentrated if released in significant quantities. Substances of denstiy < 1 would float and disperse mor ereadily. This figure is calculated from the molecular weight relative to air (28.9) Solubility in Water: LogP(o/w): This provides information on the likelihood the substance will be bioaccumulated in the environment. It is a partition ratio of fat:water Other Information: summarises information on stability, unsutable working materials, and substances to be avoided. C. Health Hazard Information Toxicological Data: lists relevant data form animal toxicological testing. Health Effects: The health effects of chemicals largely depend on their toxicity-"the capacity of an agent to produce damage to an organism (systemic or developmental), the damage may be permanent or transient". Acute Effects -Rapid onset and short duration. Usually the effect is felt immediately after a short exposure, however it can result in chronic disease. Chronic Effects slow onset and long duration. The exposure may be singular or multiple, but the adverse effects are only felt after an extended period of time.
Reversible Effects symptoms are experienced immediately after exposure but then cease rapidly. Irreversible Effects -the effects are lasting and cause considerable damage to the body, even if exposure to that chemical is stopped. A potent example is Carcinogens, which cause cells to multiply and spread out of control. Mutagens and Teratogens (which affect the development of the unborn child) are also in this category. First Aid: outlines the first aid procedures recommended in the event of an acute exposure.
First Aid Facilities: Lists specific antidotes that should be kept on hand for the particular chemical. Advice to Doctor: Remember to take a copy of the MSDS and any other relevant medical information on the chemical to the hospital. D. Precautions for Use Engineering Controls: This section advises on equipment and techniques to reduce risk of exposure. Personal Protective Equipment (PPE): This section provides information on the appropriate PPE to be used for eye, feet, hands and respiration. Handling Procedures E. Safe Handling Information Risk Phrases: These are short concise statements which describe the toxic, physiochemical and environmental effects of a substance. There are designated R1-R65 and are found on some chemical labels. Safety Phrases: Safety phrases (S1-S60) provide Storage, Handling, Personal Protective Equipment and Emergency Response advice for material. Spill and Disposal: Specifies the controls, procedures and safety requirements in dealing with leaks or spills of the material, including information on its safe disposal. The disposal information should be compatible with the HAZCHEM code and the disposal regulation in force by state and local government. Fire and Explosion Hazard: This listing documents andy hazardous decomposition products of the product during a fire, reminds the user of any flammablility/explosion hazard associated with the meterial, and gives the recommended fire fighting material. Note the relevant data under "Physical Properties" and check for compatibility with the HAZCHEM code. Reactivity Data: Gives data on the chemical reactivity including unsuitable working material and substances to be avoided. |
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