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GenAlEx
Peakall, R., Smouse, P.E., 2006. GENALEX 6: genetic analysis in Excel. Population genetic software for teaching and research. Molecular Ecology Notes 6, 288-295.

GenAlEx, short for ' Genetic Analysis in Excel', is a user-friendly cross-platform package for population genetic analysis that runs within Microsoft Excel(TM). GenAlEx enables population genetic data analysis of codominant, haploid and binary genetic data providing analysis tools applicable to plants, animals and microorganisms. GenAlEx was originally developed as a tool to assist us in our teaching of population genetic analysis, and is now widely used by university teachers and researchers around the world. In GenAlEx 6, we are pleased to introduce many new features for both teachers and researchers.

Peakall, R., Smouse, P.E., 2006. GENALEX 6: genetic analysis in Excel. Population genetic software for teaching and research. Molecular Ecology Notes 6, 288-295.
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1471-8286.2005.01155.x
Molecular Ecology Notes http://www.blackwell-synergy.com/loi/men

GenAlEx News (Posted 26-2-08)
Please note that a minor update to GenAlEx 6.1 has been posted. This version (6.1004) fixes a bug that prevented GenAlEx 6.1 from loading on some Finnish, French, Polish and Swedish systems. If you have not encountered this problem with GenAlEx 6.1, then there is no need to upgrade. If all goes to plan, GenAlEx 6.2 will be released by mid year, 2008.

GenAlEx News (Posted 20-12-07)

GenAlEx 6.1 now available!

Following almost 6 months of beta testing by registered users, we are pleased to announce the official release of GenAlEx 6.1.

GenAlEx 6.1 is an essential upgrade that replaces GenAlEx 6. In addition to minor improvements in the interface and the usual bug fixes, GenAlEx 6.1 offers some exciting new features for both teachers and researchers. For teachers, some of the new features include: more step-by-step output options, more tools for data exploration, and new tools for teaching topics such as permutation and bootstrapping. For researchers, we have considerably expanded the Analysis of Molecular Variance options to include more detailed F -statistics analysis, additional analysis outputs by locus, additional specialized permute options, additional graphing options, and the output of Linearized F st. We have also added support for Binary Haploid data, expanded the range of TwoGener options and added Nei Unbiased Heterozygosity and Nei Unbiased Genetic Distance estimates for all types of data.

GenAlEx 6.1 is fully compatible with Excel 2007. This includes the ability to take advantage of the substantially increased number of columns from 256 pre-Excel 2007 to 16,384 columns in Excel 2007. This capability will be particularly welcomed by AFLP users, whose binary data sets frequently exceed more than 256 polymorphic loci. The extra columns per worksheet will also allow expanded capability for working with DNA sequences within GenAlEx. If you intend to use GenAlEx 6.1 in Excel 2007, be sure to read the additional information provided when you download GenAlEx.

GenAlEx 6.1 now provides direct export of data to more than 20 other genetic software packages or formats including: AFLP-SURV, Alleles in Space, Arlequin, Cervus, FAMD, Famoz, Fdist2, GDA, GeneClass, GenePop, GeneticStudio, Kingroup, MEGA, MSA, MsVAr, Nexus, Phylip. POLDISP, PopGene, SPAeDI, Structure and TFPGA packages.   In addition, indirect export to other packages such as Fstat and BAPS is available via the GenePop export format.

Thank you for using GenAlEx 6.1. Enjoy!

Rod Peakall and Peter Smouse

Previous News


A new Master of Molecular Genetic Analysis at the Australian National University

Gathering genetic data is becoming faster and easier, now we need new ways to analyse the data. Skills in molecular genetic analysis are crucial.

The new Master of Molecular Genetic Analysis builds on a series of highly successful national graduate workshops on population genetic analysis offered by the authors of GenAlEx over the past decade. It provides a unique blend of theoretical knowledge, laboratory skills, and computing techniques - arming students with the intellectual tools they will need to design, carry out and interpret molecular genetic analysis.

The one year long program is open to graduate students with a Bachelor of Science or equivalent with a major in the field of biological sciences with relevant experience or honours, and will be of particular interest to graduate students from Australasia and the nearby Asia and Pacific regions.

The program begins in February 2008, with applications still open for 2008 (but closing soon).

For more information about the Master of Molecular Genetic Analysis program please see:
http://www.anu.edu.au/BoZo/discover.php

Special new features for teaching

  • More than 20 different kinds of graphs to summarise data analysis.
  • An intuitive and consistent user interface with context-dependent dialog boxes to guide students.
  • Several tools designed specifically for teaching students.

Special new features for research

  • Tools for importing, editing and manipulating raw genotype and sequence data from automated sequencing or genotyping software.
  • A diverse range of tools for data exploration.
  • New 2D spatial autocorrelation procedures in addition to the existing wide range of spatial analysis options.
  • Estimation of pairwise relatedness among individuals.
  • Tools for genetic tagging applications, including location of matching genotypes and calculation of probabilities of identity.
  • Tools to assists users keep track of data analysis.
  • Data export options to other population genetic software packages.

Documentation

  • A comprehensive independently written guide.
  • A summary of the methods, statistical formulae and supporting references.
  • Background to the spatial autocorrelation analyses offered.
  • Flow charts illustrating procedures and pathways of analysis.

Computer requirements
GenAlEx is written in Visual Basic for Applications within Microsoft Excel (TM) and is compatible with Excel 97 upwards under Microsoft Windows(TM) and Excel 98 upwards on the Macintosh (TM). GenAlEx 6 has been extensively tested in Excel 2003 within Windows XP (TM), and in Excel 2004 within OS X on the Macintosh (TM).


Disclaimer
This program is provided free of charge by the authors. While every effort has been taken to ensure the accuracy of the results and the smooth operation of the program, we regret that we are unable to take responsibility for unintentional errors or problems that may be encountered by users. We are also unable to provide individualized support for users of the program.


Authors
Professor Rod Peakall
School of Botany and Zoology
The Australian National University
Canberra ACT 0200
Australia
Email: rod.peakall@anu.edu.au

Professor Peter Smouse
Department of Ecology, Evolution and Natural Resources, Cook College
Rutgers University
New Brunswick NJ 08901-8551 USA
Email: smouse@AESOP.Rutgers.edu


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